血小板削减症的发病机理(国外英文资料).docVIP

血小板减少症的发病机理(国外英文资料) The pathogenesis of thrombocytopenia Normal platelets number is 100-300, if below this number is can be called thrombocytopenia, the patients body once collision will appear bruises, if the number of platelets less than 50 will have subcutaneous bleeding, the following is the introduction to the pathogenesis of thrombocytopenia. Thrombocytopenia usually refers to thrombocytopenic purpura, but there may be other causes, too. Platelets are low in origin: 1, is insufficient production of platelets in the body, such as bone marrow, a patient with aplastic anemia, drugs lead to damage of bone marrow, blood cancer (leukemia), or other cancers, etc.; Platelets are consumed too fast, such as immunological thrombocytopenia, the most common form of thrombocytopenia. The general symptoms of low platelets are subcutaneous and mucosal areas such as nose and mouth teeth, which can cause swelling in the joints. Low blood platelets can be tested by blood tests, and if a patient deteriorates in a short period of time, it may be a result of blood cancer. If found in time, the appropriate treatment may be provided, and the condition may not worsen. Thrombocytopenic purpura is primary and secondary. Primary thrombocytopenic purpura is an immunological synthesis and is a common hemorrhagic disease. It is characterized by the presence of antiplatelet antibodies in the blood circulation, which causes the platelets to destroy too much and cause purpura. In the bone marrow, the giant nuclear cells are normal or increase, infantile. Clinical can be divided into acute and chronic two kinds, the two pathogenesis mechanism and the performance have significant difference. Idiopathic thrombocytopenic purpura is caused by excessive platelet destruction associated with megakaryocyte maturation disorder caused by acquired hemorrhagic disease, also known as idiopathic thrombocytopenic purpura. For more than 85% of the cases of serum platelet surface or IgG antibody, because of th