rna剪接与疾病.pptxVIP

RNA splicing and diseases;The mechanism of RNA splicing;RNA mediates the transmission of genetic information;Prokaryotic genes generate continuous mRNAs;Some eukaryotic genes generate pre-mRNAs with coding exons interrupted by non-coding introns;RNA splicing removes introns from a pre-mRNA and joins adjacent exons ;Schematic demonstration of the experiments that identified adenovirus split genes (interrupted genes);Abnormal splicing of the beta-globin gene leads to beta-thalassemia（β-地中海贫血）, an anemia prevalent primarily in some Mediterranian countries ;RNA剪接的识别位点及分支点 ;图示RNA剪接的识别位点以及分支点;Exo