rna干扰rnainterferencernai.pptxVIP

RNA干扰（RNA interference, RNAi）——The Nobel Prize in Physiology or Medicine 2006;热点问题;基因默化現象;简介;发现过程重大事件;获奖人物介绍;矮牵牛花实验;;反义RNA抑制实验;Fire and Mello sent their study named Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans to Nature in 1998. Although that paper didn’t further explain the mechanism of RNA-mediated interference, it was a foundation of RNAi research and finally they found the answer in the follow-up study. ;Their study mainly involved three part.;2.Is the phenotype produced by interference using dsRNA specific?;3. Could the dsRNA-mediated interf