自在基与细胞毁伤(国外英文资料).docVIP

自由基与细胞损伤(国外英文资料) Free radicals and cell damage Free radicals, chemically called free radicals, contain an atomic mass that is not an electron. Because the atoms to form molecules, chemical bonds in the electronic must come in pairs, so free radicals are priceless seize an electron, and other substances to form stable substance. Free radicals are transient forms of atoms or functional groups that dont contain electrons, and are generally present in biological systems. These include oxygen free radicals (such as hydroxyradical OH), hydrogen-free radicals (H), carbon free radicals, lipid free radicals, and the chemical properties of ooh are the most active. Our biological system is the chief of oxygen free radicals, such as superoxide anion free radical, hydroxyl radical and lipid oxygen free radicals, nitrogen oxide and nitric oxide free radical. Plus hydrogen peroxide, single-line oxygen and ozone, known as reactive oxygen. There are also free radicals in the human body, and there are two aspects of their production: one is the high temperature, radiation, photopolysis, chemicals and other exogenous free radicals in the environment. The second is the endogenous free radicals produced by various metabolic reactions in the body. Endogenous free radicals are the main sources of free radicals in the human body, and the main pathways are caused by the leak of the mitochondrial respiratory chain. The hydroxygenation is produced by the multifunctional oxidase (MFO) of the peroxidase body. In addition, the body hemoglobin and myoglobin can also produce free radicals through non-enzymatic reactions. Free radicals in the body can help deliver energy that sustains life, can also be used to kill bacteria and parasites, and can also be involved in eliminating toxins. Controlled free radicals is beneficial to human body, but when free radicals in the body over a certain amount, and out of control, the free radicals will bring harm to our life. The damage caused by normal cells an