浙江大学马成有机化学乙课件 要点.pdfVIP

Organic Chemistry (Carey 5th) CHAPTER 1 Introduction: Structure Determines Properties 1. Concepts: ① Atom, Electron and Orbital ② Ionic, Covalent, Polar Covalent Bond / Electronegativity ③ Lewis Structures/ Formal Charge/ Resonance ④ The Shapes of Molecules ⑤ Hybridization ⑥ Inductive effect ⑦ Theory of acid and base including Conjugate Acids Bases/Lewis base acid/ Brǿnsted base acid CHAPTER 2: Hydrocarbon Frameworks. Alkanes and Cycloalkanes 1. Concepts: ① Nomenclature and Conformational Analysis (IUPAC nomenclature involving spirocyclic and bicyclic compounds, Ethane, Butane, Cyclohexanes and Decalin conformation analysis, Ring strain) ② Diagrams--include Newman projection, Wedge-dash, Sawhorse diagrams ③ Reaction Classification/ Reaction Variables/ Reactive Intermediates (cation, anion, radical, carbene) ④ Structures of Carbocation/ Radical/ Carbanion ⑤ Reaction mechanism in general: Bond cleavage Models/ Activation Energy, Reaction Heat/ Thermodynamic Control and Kinetic Control/ Hammond Postulate 2. Reaction: ① Radical Monohalogenation of alkane, Meachanism ② Reaction rate/ Calculating the amounts of products ③ General Selectivity of Radical Halogenations ( α-position of unsaturated compound: CH-C=C; CH-C 三CH) CHAPTER 3: Stereochemistry 1. Concepts: ① Isomers: Stereoisomers/ Configurational Stereoisomers of Alkenes/ Chirality (Plane of Symmetry), Optical Activity ( DL), Stereocenter ② Fischer Projections ③ R or S Configuration (Cahn-Ingold-Prelog R/S Notation) ④ Racemic mixture; Meso-compound; Diastereomers and Enationmer (including Erythro and Threo enatiomers) ⑤ Properties of Stereoisomers, Resolution ⑥ Simple compounds with stereo-