不同部位接种b型流感嗜血杆菌结合疫苗不良反应比较.pdfVIP

现代临床护理（Modern Clinical Nursing）2013.12（4） 19 不同部位接种 b 型流感嗜血杆菌结合疫苗不良反应比较 林 文璇 ，张桂辉 ，王馨 ，吴婕翎 姚 晓敏 （广东省妇幼保健院，广东广州，510010） ［摘要］　目的　探讨不同部位接种 b 型流感嗜血杆菌结合疫苗（ haemophilus type b conjugate vaccine，Act-Hib）不良反应 情况。方法　将 500 例预防接种 Act-Hib 的 2～8 月龄婴幼儿随机分为实验组与对照组，每组各 250 例，分别于大腿前外侧肌 和上臂三角肌进行疫苗接种。比较两组婴幼儿接种后局部及全身反应情况。结果　实验组婴幼儿局部反应程度明显轻于对 照组，两组比较，差异具有统计学意义（ ＜0.05）。结论　婴幼儿预防接种 Act-Hib，在大腿前外侧肌注射接种局部反应程度明 P 显轻于在上臂三角肌注射。 ［关键词］　b 型流感嗜血杆菌结合疫苗 ; 预防接种；不良反应 ［中图分类号 ］　R47 1　［文献标识码 ］　A　［文章编号 ］　 167 1-8283 （20 13）04-00 19-03　［DIO］　 10.3969/j .issn.167 1-8283.20 13.04.06 The adverse reactions of the haemophilus type b conjugate vaccine injected at different parts Lin Wenxuan，Zhang Guihui，Wang Xin，Wu Jieling，Yao Xiaomin ∥ Modern Clinical Nursing，-2013，12（4）：19. ［Abstract］　Objective　To investigate the adverse reactions of the haemophilus influenza Type B vaccine（Act-Hib）．Methods　 500 infants aged 2-8 months were randomly divided into the experimental and control groups in equal number： The infants in the former group received vaccination by injecting （Act-Hib）in anterolateral thigh and those in the control in the upper arm deltoid muscle． The adverse reactions in the two groups were observed and compared．Results　The incidence of local response in the experimental group was lower than that in the control group （ ＜0.05）．Conclusion　The incidence of adverse reaction by injecting Act-Hib in the P anterolateral thigh is lower than that in the upper arm deltoid muscles for the infants aged 2-8 months undergoing vaccination of Act-Hib． ［Key words］ 　haemophilus Type B conjugate vaccine;vaccination； adverse reaction b 型流行性感冒嗜血杆菌（haemophilus influe nza 着处皮肤，肌内注射接种部位为上臂外侧三角肌中