乳腺癌患者血清CA15-3和CEA联合检测的临床价值.pdfVIP

VÐι42， No.2 第 42 卷第2 期 哈尔吉骂医科大学学报 186 双脚年4 月， JOU民NAL OF HARBIN MEmCAL UNIVERSITY Apr.，组脚 乳腺癌患者血清 CA15-3 和 CEA 联合 检测的临床价值 贺丽雅，苗杰\孙淑芳 (1.哈尔滨医科大学第一l临床医学院核医学科，黑龙江哈尔滨 15刷1 ; 2. 哈尔滨市社会保险事业管理局医院，黑龙江哈尔滨 15∞30) [摘票] 耐伪 评价乳腺癌患者lÓl.清 CA15帽3 和 CEA 的临床价值。方旅 对422 例良恶性乳腺疾病患者进行血清 CA15-3 和 CEA 的测埠。佛兽 良性疾病和未转移乳腺癌患者的血清 CA15-3( 3OU/mL)和 CEA( 15ng1n也)阳性率 较低，已有转移或复发的乳腺癌患者血清 CA15-3 的敏感性为75 1品， CEA 的敏感性为 339品， CA15-3 值升高要比临床 谚断早。储份血清CA15-3 和 CEA 对巩腺癌的敏感性不明显。血清 CA15-3 和 CEA 的值同时持续升高或保持阳 性，应当考虑诊断乳腺痛有转移或复发。 CA15-3 比其他脏测指标敏感性高。 [关键词] 乳腺癌;血清糖蛋白抗体 15-3; 癌胚扰服 {中图分类号] R737.9 [文献标识码] A [文章编号] 1删-1师(2刷)出-01协但 Oinical value of sennn CA15-3 and CEA in patien也 wi由 brl侃st cancer HE Li….ya ,MIAO Jie ,SUN Shu-far骋， et al (战归rtmenl 0/Nuclear Medic仰，而e First αinical College ,Harbin Medical Unù Abs旬8ct: Objective To evaluate the clinical value of CA15-3 and CEA in p咄咄tswi由 breast cancer. Me伽州s Senun levels of CA15-3 and CEA were detemñned in 422 p硝ents wi出 beni伊1 and malignant breast diseases. RJ翩翩The positive rat闹。f CAI5-3( 30U/mL) and CEA( 15咐mL) were lower in patients with be时伊 and without metastatic 加:ast cancer. 币le sensitivities of CA15-3 and CEA in patients with meta帽 剧lic and 阳刚旧时 breast cancer was 75% in CA15-3 and 33% in CEA. CA15-3 increased before 由e clini- cal dia阴阳s. Conclusion The sensitivities of senun CA15-3 and CEAωbreast cancer are not ap阳rent. The metastasis and 阳沈阳ITence of breast cancer should be considered while senun CA15-3 皿d CEA íncrease at the 阳me time or are persis阳t 阳itive. The sensitivity of CA15-3 is higher than 0出er index四. Key words: breast cancer; 叫nc