theantitumorpropertiesofanontoxic,nitricoxide–modified.pptVIP

The antitumor properties of a nontoxic, nitric oxide–modified version of saquinavir are independent of Akt by Danijela Maksimovic-Ivanic, Sanja Mijatovic, Djordje Miljkovic, Ljubica Harhaji-Trajkovic, Gordana Timotijevic, Marija Mojic, Darrin Dabideen, Kai Fan Cheng, James A. McCubrey, Katia Mangano, Yousef Al-Abed, Massimo Libra, Gianni Garotta, Stanislava Stosic-Grujicic, and Ferdinando Nicoletti Mol Cancer Ther Volume 8(5):1169-1178 May 5, 2009 ?2009 by American Association for Cancer Research Cytotoxicity of Saq-NO versus Saq; Saq-NO reduces the viability of tumor but not primary cells. D