中西医结合治疗强直性脊柱炎的系统评价.pdfVIP

成都中医药大学2006 级硕士论文 ABSTRACT Objectives To Assess the efficacy of the Chinese herbal with west medicine in patients with ankylosing spondylitis(AS) by the methods of EBM,and provide the evidence for the treatment of the Chinese herbal with west medicine in patients with AS. Methods We searched the Cochrane Controlled Trials Registe (CCTR) ( The Cochrane Library issue 4 2008) MEDLINE(1997to2008), and China National Konwledge infrastructure (CNKI),Chinese Biological Medicine database(CBM),WanFang database.The Chinese journals related to TCM in 2008 searched by hand .Two authors independently assessed trial quality and extracted data from these Randomized Controlled Trails, then imported them into the Mete-analysis by Rev.Men 4.2.10. Results 20 studies (1571 patients) were identified. The results of Mete-analysis indicated: there are evidences to support that using Chinese herbal with west medicine is better than SSZ only on symptom、physical sign、Erythocyte Sedimentation rational （ESR）、 C-reactive protein （C-RP）、physi-cal function、pain、spinal mobility、 Bath AS patient global score （BAS-G) and Bath AS functional index （BASFI）.but the methododlogical quality is low in these studies. Conclusions By the result of this study, the Chinese herbal with west medicine is more effective than simplex west medicine. However, the evidence is not enough strong because of the low qualities of trials, the small sample sizes and other defect. Kedwords The Traditional Chinese Medicine Prescription； Ankylosing SpondylitisSalazosulfapyridine ； Randomized Controlled Trail；Meta-analysis；