抗恶性肿瘤药-魏尔清幻灯片.pdf

Chapter 4 Chapter 4 Antineoplastic drugs Antineoplastic drugs 抗恶性肿瘤药 抗恶性肿瘤药 Pharmacological basis Pharmacological basis Typical antineoplastic drugs Typical antineoplastic drugs Common toxicity and rational use Common toxicity and rational use Cancer cell growth in the tissue Cancer cell growth in the tissue kg kg g g mg Palliative mg Palliative chemotherapy chemotherapy 姑息性化疗 姑息性化疗 Curative Curative chemotherapy chemotherapy 治愈性化疗 治愈性化疗 Part A Part A The pharmacological basis of The pharmacological basis of antineoplastics antineoplastics Part A. The pharmacological basis of Part A. The pharmacological basis of antineoplastics antineoplastics • 1. Classification of antineoplastics • 1. Classification of antineoplastics • 1.1 Classification according to chemical structure • 1.1 Classification according to chemical structure and source and source • (1) Alkylating agents (烷化剂: 氮芥类等) • (1) Al