右旋美托咪啶和可乐定在硬膜外麻醉妇科手术中的比较_张彭玮.pdfVIP

2012 16 5 Jour al of Cli ical Medici e i Practice ·85 · 张彭玮, 孙　哲, 延柏文, 葛亚萍, 刘　冬, 白耀光 ( , , 718600) 　　　:　。　 100 , 2:+(RD )+(RC )。 RD 0.75% 17 m L+(1.5 μg/kg), RC 0.75% 17 m L+(2 μg/kg )。、 、。　RD RC ;RD RC ;2。　。 :;;;; + :R 614.4 2　　:A 　　:1672-2353(2012)05-0085-03 Comparison of dexmedetomidine and clonidine in gynecologic surgery under epidural anesthesia ZHANGPeng-wei, SUN Zhe, YAN Bai-wen, G Ya-ping, LIU Dong, BAI Yao-guang (Dingbian P eop le′s Hosp ita l, Yu lin , S hanx i, 718600) 　　ABSTRACT:Objective　To compare the effects of dexmedetomidi e a d clo idi e o the pa- tie ts receivi g gy ecologic surgery u der epidural a esthesia.Methods　A total of 100 adult female patie ts u dergoi g vagi al hysterectomies u der epidural a esthesia w ere ra domly divided i to ropivacai e plus dexmedetomidi e (RD)group (n =50)a d ropivacai e plus clo idi e (RC)group (n =50).RD group received 0.75%epidural ropivacai e 17 mL a d dexmedetomidi e1.5 μg/kg, w hile RC group received admixture of 17 mL 0.75%ropivacai e a d 2 μg/kg clo idi e.The time of a algesia, the levels a d duratio of se sory a d motor block, the sedatio score, a d postopera- tive adverse reactio s were observed.Results　Sedatio scoresw ere higher i the RD group tha i the RC group.The ropivacai e dose was less i the RD group tha i RC group.The adverse reac- tio s w ere a slightly higher i cide ce of ausea a d dry mouth i both groups.Conclusion 　 Dexmedetomidi e is a better adjuva t of a esthesia compared with clo idi e for epidural a esthesia. K Y　WORDS:clo idi e;dexmedetomidi e;ropivacai e;epidural a esthesia;vagi al hys- terectomy 　　2009 [2]