施国跃 BB 2012 AuNPs@SiO for DA.pdfVIP

Biosensors and Bioelectronics 38 (2012) 270–277 Contents lists available at SciVerse ScienceDirect Biosensors and Bioelectronics journal homepage: /locate/bios A novel electrochemical sensor for determination of dopamine based on AuNPs@SiO2 core-shell imprinted composite Dajun Yu a, Yanbo Zeng a,b, Yanxia Qi a, Tianshu Zhou c, Guoyue Shi a,n a Department of Chemistry and Shanghai Key Laboratory of Green Chemistry and Chemical Process, East China Normal University, 500 Dongchuan Road, Shanghai 200241, PR China b College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, PR China c Department of Environmental Science, East China Normal University; 500 Dongchuan Road, Shanghai 200241, PR China a r t i c l e i n f o a b s t r a c t Article history: A novel core-shell composite of gold nanoparticles (AuNPs) and SiO2 molecularly imprinted polymers Received 7 April 2012 (AuNPs@SiO2-MIPs) was synthesized through sol–gel technique and applied as a molecular recognition Received in revised form element to construct an electrochemical sensor for determination of dopamine (DA). Compared with 26 May 2012 previous imprinting recognition, the main advantages of this strategy lie in the introduction and Accepted 31 May 2012 combination of AuNPs and biocompatible porous sol–gel material (SiO2). The template molecules (DA) Available online 12 June 2012 were firstly adsorbed at the AuNPs surface due to their excelle