分子生物学1(蛋白组学).ppt

Figure 6. Triple SILAC Pulldowns Revealing Histone Modification Crosstalk Three-dimensional representation of the MS signal of an Sgf29 peptide identified in a triple pulldown SILAC experiment (the m/z scale is the x axis, the chromatographic retention time is the y axis, and the MS-signal is the z axis). Each group of signals represents the natural isotope pattern of the peptide. The relative intensities of the triplet peak of the Sgf29 peptide indicates the preference of binding to the modification states (unmethylated histone H3 peptide [left peak], H3K4me3 peptide [middle peak], and the d