应用PDCA循环干预我院PCI患者围术期预防用抗菌药物地效.PDFVIP

应用PDCA 循环干预我院PCI 患者围术期预防用抗菌药物的效 果分析 ＊ # 张晓娟 ，刘晓琦，杨 敏（广东省人民医院·广东省医学科学院药学部，广州 510080） 中图分类号 R969.1；R978.1 文献标志码 A 文章编号 1001-0408（2014）46-4340-03 DOI 10.6039/j.issn. 1001-0408.2014.46.08 摘 要 目的：探讨PDCA 循环对经皮冠状动脉介入治疗（PCI ）患者围术期预防用抗菌药物的干预效果。方法：应用PDCA 循环 对我院PCI 围术期预防用抗菌药物作持续性干预。将干预前随机抽查的PCI 病例作为对照组，第一阶段干预后抽查的PCI 病例作 为干预1组，第二阶段干预后抽查的PCI 病例作为干预2组，将3组预防用抗菌药物使用情况进行比较分析。结果：与对照组相比， 干预后我院PCI 围术期预防用抗菌药物使用率由97.50％分别下降至7.50％、1.00％，具有显著性差异（P ＜0.01）；干预1组和干预2 组平均抗菌药物费用及抗菌药物费用占总药品费用的百分比均明显下降，而术后感染发生率并未增加。结论：PDCA 循环能够促 进PCI 围术期预防用抗菌药物的合理性，建议在抗菌药物的管理中推广应用PDCA 循环，以促进临床合理用药。 关键词 PDCA ；预防用抗菌药物；经皮冠状动脉介入治疗；干预 Analysis of Intervention Effect of PDCA on Antibiotics for Prophylactic Use in PCI Patients of Our Hospital ZHANG Xiao-juan ，LIU Xiao-qi ，YANG Min （Dept. of Pharmacy ，Guangdong Provincial People ’s Hospital Guangdong Academy of Medical Science ，Guangzhou 510080，China ） ABSTRACT OBJECTIVE ：To investigate the intervention effect of PDCA on perioperative prophylactic application of antibiotics in percutaneous coronary intervention （PCI ）patients of our hospital. METHODS ：PDCA was applied for continuous intervention to perioperative prophylactic application of antibiotics in PCI patients of our hospital. PCI cases were randomly sampled before inter- vention as control group. PCI cases were sampled after first stage of intervention as intervention group 1；and were sampled after second stage of intervention as intervention group 2. The prophylactic application of antibiotics were analyzed and compared among 3 groups. RESULTS ：Compared with control group ，the utilization ratio of antibiotics for perioperative prophylactic use decreased from 97.50％to 7.50％and 1.00％，respectively ；there was significant difference （P ＜0.01）. Average antibiotics cost and ratio of antibiotics cost to drug cost decreased significantly in intervention groups ；while