细胞生物学(翟中和第四版)第1章绪论.pptVIP

Thank you! 图片来源 /cells/animals/animalmodel.html /wiki/Cell_biology * 背景音乐：小城故事片段（邓丽君） 类比一个细胞和这座岛上的小城 教材四部分主要内容： 细胞基本知识介绍（1-3章） 细胞的基本结构与功能（4-12章） 细胞重大生命活动（13-17章） 细胞的社会联系（17章） * The key to every biological problem must finally be sought in the cell, wrote the great classical cell biologist, E.B. Wilson, in 1925. Yet at the time Wilson wrote, the world inside the cell was largely inaccessible. The primary instrument of investigation for classical cell biologists--the light microscope--was physically incapable of resolving a cells fine interior details. Long ago it became evident that the key to every biological problem must finally be sought in the cell; for every living organism is, or at some time has been, a cell.“ E.B. Wilson (1925) The Cell in Development and Heredity 3rd edition Macmillan Inc. Edmund Beecher Wilson (19 October 1856 – 3 March 1939) was a pioneering American zoologist and geneticist. He wrote one of the most famous textbooks in the history of modern biology, The Cell in Development and Inheritance. * * * The inner life of the cell 是哈佛大学分子和细胞生物学系委托 XVIVO 公司为其 BioVisions at Harvard program 制作的系列教学动画之一。这部八分钟的动画旨在增进该系本科生对生命科学的理解深度。 The animation illustrates unseen molecular mechanisms and the ones they trigger, specifically how white blood cells sense and respond to their surroundings and external stimuli. 本片具体描述了白细胞的“内部”世界：收到信号后，细胞膜上的细胞粘联分子（CELL ADHESION MOLECULES）很快识别血管壁上的同类分子，使白细胞停靠在血管的内壁上。与此同时，一些其他分子结合到细胞膜上的受体（RECEPTOR），引发了白细胞内的巨大反应：组成细胞骨架的小分子 ACTIN和MICROTUBE被重新组装；细胞核内部合成新的RNA并且把他们送到细胞核外，然后作为模板，在内质网上合成出来蛋白质，这些蛋白质在高尔基体的加工车间里加工包装后，被运往细胞的各个地方。tranporter先生MYOSIN，拖着个巨大的囊泡。最终使白细胞从圆的变成扁的，穿越内皮细胞间隙。 * 图片来源：/cells/nucleus/chromatin.html * 图片来源：/nrm/journal/v5/n4/fig_tab/nrm1358_F2.html Controlled cell death, plant survival and development. Nature Reviews Molecular Cell Biology 5, 305-315 (April 2004) a | In the hypersensitive response, chromatin condensation and DNA cleavage into 50-kb fragments were observed before the apparent disruption of the