椎体后凸成形术近期临床疗效评估及远期非手术椎体新发骨折的相关因素分析.pdfVIP

椎体数目多（OR=9.682）及长期使用糖皮质激素（OR=9.584）是术后非手术椎体新发骨折的高 危因素。 结论： 椎体后凸成形术在治疗老年骨质疏松椎体压缩骨折近期疗效显著，能立即稳定伤椎，起到 迅速止痛作用；由于球囊的扩张作用，恢复了椎体的高度，纠正了由于椎体压缩导致的脊柱后 凸畸形，同时降低了骨水泥渗漏的几率。远期术后非手术椎体新发骨折的出现影响因素可能是 多方面的，骨质疏松程度重、手术强化椎体数目多及长期使用糖皮质激素可能是引起术后非手 术椎体新发骨折的高危因素。 关键词 骨质疏松椎体压缩骨折 椎体后凸成形术 非手术椎体再骨折 2 Abstract Objective: To investigate clinical observation on the curative effect of percutaneous kyphoplasty of osteoporotic vertebral compression fracture (OVCF) and the associated factors of non-surgical vertebral re-fracture .Method: The clinical data of 102 patients who underwent PKP for osteoporotic vertebral compression fracture from January 2005 to December 2009 in our center were retrospectively studied. The changes of visual analogue scale of pain (VAS), vertebral height and Cobb angle were observed on X ray before and 3 days after the operation. The complications such as cement ledge were record. Observation the follow-up results, the patients were divided into fracture group and non-fracture group (control group) by whether there was a new fracture. The differences between the two groups in general information(sex, age, bone mineral density, number of preexisting fracture, degree of vertebral compression, existence of scoliosis and Cobb angel), operating factors(augmentation number of vertebral, operative approach, cement volume, Disc cement leakage, degree of vertebral height restoration), history of trauma and long-term use of glucocorticoids were analyzed . One-way analysis of variance (ANOVA) and chi-square test was used to analyze the correlation between the above factors and non-surgical vertebral fracture. All relevant factors were introduced to Logistic Regression Analysis to analyze the main factors of