重视细菌检验在抗感染中的作用_培训课件.pptVIP

* * * * * * * * The first outbreak of KPC-producing K pneumoniae outside the USA was from Israel (figure 2).17 A single KPC-3-producing K pneumoniae clone and several KPC-2-producing K pneumoniae clones are responsible for ongoing outbreaks in Tel Aviv hospitals. The KPC-3-producing strain from Israel is genetically linked to those reported in the USA, suggesting strain exchange by travellers and patients between Israel and the USA * * 谢谢！ 浙一医院肺炎克雷伯菌对碳青霉烯类抗生素敏感率 碳青霉烯类耐药机制 孔道蛋白丢失 外排泵 碳青霉烯酶 金属酶：IMP、VIM、GIM、NDM等 A类丝氨酸酶： KPC、GES-2等 D类丝氨酸酶： OXA-23等 碳青霉烯酶的主要生化特性 注：○：高水平；□：低水平；△：不水解 1 K.pneumoniae A