化脓性骨髓炎(国外英文资料).docVIP

化脓性骨髓炎(国外英文资料) Acute hematogenous osteomyelitis Etiology: hemolytic Staphylococcus aureus is the most common pathogenic bacteria, Streptococcus accounted for second, a bloodthirsty influenza Bacillus also can cause disease. Other bacteria were Escherichia coli and Clostridium perfringens, but also pneumococcus and Staphylococcus aureus. Pathogenic strains of the disease through hematogenous spread, first infectious lesions in other parts of the body, generally located in the skin or mucous membranes, such as furuncle, carbuncle, tonsillitis and otitis media. If the primary lesion is not treated properly or the body resistance decreases, bacteremia or sepsis can be caused by bacteria entering the blood circulation. When the thrombus enters the nutrient artery, it is often obstructed by the capillary in the metaphysis of the long diaphysis. The reason is the slow blood flow, easy to make bacteria stagnate; small children near the epiphyseal plate end arteries and capillaries are more curved and become rich and the vascular loops, blood flow is slow, the bacteria more easily deposited, so children metaphysis as the primary site. Before the onset, there is often a history of trauma. Children often knock, so the true meaning of trauma is unknown, probably due to local trauma tissue trauma and bleeding, easy to disease. Trauma may be the cause of the disease. The onset of the disease, and living conditions and health status in previous years, the incidence rate was significantly higher than that of rural city, in recent years in the big coastal city, hematogenous osteomyelitis is rare, but in remote areas, the disease is common disease. Pathology: the pathological changes of the disease are destruction of bone and formation of dead bone. Later, there are new bone and become bony shell. A large number of bacterial emboli stop at the metaphysis of the long bones, blocking small vessels and rapidly producing osteonecrosis, with congestion, exudate, and infiltration of leukoc