软肝抗纤方抗肝纤维化的临床观察及其机理研究.pdf

(P0．01)，且明显低于秋水仙碱组(190．68±23．35)(P0．05)。 结论： 1、软肝抗纤方能显著改善患者临床症状，显著改善肝功能，并能明显降低血清 肝纤维化标志物水平。表明软肝抗纤方对肝纤维化有明显的治疗作用。 2、软肝抗纤方药物血清能抑制HSC的增殖与胶原蛋白的分泌，这可能是其治疗 肝纤维化的作用机理之一。 关键词；软肝抗纤方，肝纤维化，肝星状细胞，细胞增殖，胶原分泌 ThecIinicaIobserveand mechanicaIof partiaI study the of Liverand compIexprescriptionsoftting in S anti—fibrosiS fibrosi anti—Hepatic Ofthe icationofChineseMedicifieandWestern SpeciaIity：InternaIcompI Medicine Author：WuXiumei Tutor：Zhou Fusheng Objective： fibrosiswhichisadiffusionlesionformedoneormore Hepatic hepatic by or isan actions etiopathogenisises’Slong repeated importantpatho— elementin liverdiseases’S resultis component many growthprocess，whose cirrhosiswhichhazardsthe health the hepatic people’S seriously．Now curativeeffectofWesternmedicineto fibrosisisn’tideal．Butthe Hepatic multistrataandmultitudeand and combination polynucleationpolyrake contributionisthecharacteristicof pharmacology complexprescription traditionalChinesein makesit the fibrosis，which druganti—Hepatic having in and and the fibrosis wide ascendancypreve