卒中诊疗新策略-培训课件.pptVIP

目前，对氧化应激与疾病的相关性研究已经发现，氧化应激是心脑血管疾病、糖尿病、免疫性疾病、神经系统疾病等众多疾病的重要发病机制。 备注： 8-羟基脱氧鸟苷 (8-hydroxy-2’-deoxyguanosine,?8-OHdG)，是敏感的DNA损害标志物。 * REGICOR研究是一项以普通人群为基础的横断面研究，共纳入西班牙赫罗那市4782名年龄25-74的受试者。 排除其中拒绝随访、患症状性心脏病、搬出地区以及疾病晚期后纳入4042名受试者， 随机检测其中2793 名受试者的oxLDL水平，随访10年 无CAD事件者基线时oxLDL水平53.2U/L，有CAD事件者65.1U/L,(P＜0.001） Mean age was 50.0 (13.4) years, and 52.4% were women. There were 103 CAD events (34myocardial infarction, 43 angina, 26 coronary deaths), within the framework of the REGICOR study [13]. Participants who declined follow-up, or who already had symptomatic heart disease at study inclusion, or who