心血管药物Cardiovasculardrugs讲述.pptVIP

* * * * * * * * * * * * * * * MAO抑制剂可阻抑Guanazodine的正常代谢 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * After a drug is swallowed, it is absorbed by the digestive system and enters the hepatic portal system. It is carried through the portal vein into the liver before it reaches the rest of the body. The liver metabolizes many drugs, sometimes to such an extent that only a small amount of active drug emerges from the liver to the rest of the circulatory system. This first pass through the liver thus greatly reduces the bioavailability of the drug. * * * * * * 卡尼：乙酸苯胺类 * * * *