复方补肾中药对去卵巢大鼠骨质疏松作用的影响论文.docVIP

　　复方补肾中药对去卵巢大鼠骨质疏松作用的影响论文 .freely rats and study its mechanism. Methods Adult ovariectomized rats odel of postmenopausal osteoporosis. After being fed odel, the general BMD in treated groups increased significantly (P 0.01) ized rats female rats osteoporosis induced by ovariectomy. One of the mechanisms enopausal；IL-1；IL-6；TNF-α；animal model；drug of kidney invigoration 绝经后骨质疏松症(PMOP)是由雌激素减少所致的骨质疏松,随着细胞生物学和分子生物学研究的不断深入,骨髓微环境中细胞因子的作用越来越受到人们的重视。为进一步探讨补肾中药防治骨质疏松的作用机理,本研究通过切除大鼠卵巢建立骨质疏松动物模型,观察复方补肾中药对去卵巢大鼠骨质疏松的作用,并通过其对骨组织中白细胞介素(IL)IL-1β、肿瘤坏死因子(TNF-α)和IL-6的影响探讨补肾中药的作用机理。 1 实验材料 1.1 动物 三月龄SD雌鼠50只,