首次实现五光子泵浦受激发射-simultaneousve-photon.PDFVIP

ARTICLES PUBLISHED ONLINE: 27 JANUARY 2013 | DOI: 10.1038/NPHOTON.2012.344 Frequency-upconverted stimulated emission by simultaneous five-photon absorption Qingdong Zheng , Haomiao Zhu, Shan-Ci Chen, Changquan Tang, En Ma and Xueyuan Chen * * Since the invention of the laser in 1960, multiphoton effects have become useful in techniques for real applications as well as conceptual predictions. Here, we report the first experimental observation of frequency-upconverted stimulated emission from a novel fluorophore through simultaneous five-photon absorption. Compared to lower-order nonlinear absorption, the fifth-order dependence on input light intensity of the five-photon absorption process will provide much stronger spatial confinement, allowing the achievement of a much higher contrast in imaging. Stimulated emission has also been achieved by the absorption of two to four photons under near-infrared laser excitation, making this gain medium a promising multiphoton imaging probe with attractive features, including the absence of autofluorescence from biological samples, large penetration depth, and improved sensitivity and resolution. lthough, being a third-order process, two-photon absorption materials for multiphoton excited lasing (or stimulated emission) (2PA) is several orders of magnitude weaker than linear should not only have large MPA cross-sections—they should also A absorption, in the past two decades the use of lasers has have small non-radiative decay rates. Over the past decade, several led to significant progress in various two-photon-related applications. molecular design strategies have been developed for p-conjugated These