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* Depression in Older People Guanglei Xun Mental Health Center of Shandong Province * Introduction of Depression(1) Difinition of depression Depressive disorder is characterized by depressed mood that is out of keeping with the circumstances. It may vary from low mood to melancholia, or even stupor. In severe cases, psychotic symptoms such as delusions and hallucinations may be present. Anxiety and motor agitation may be more prominent than depression in some cases. * Introduction of Depression(2) Core symptoms Depressed mood Loss of interest or pleasure Decreased energy, increased fatigue Additional symptoms Loss of confidence Inappropriate and excessive guilt Recurrent thoughts of death, suicidal thoughts or behaviour Diminished evidence of ability to think or concentrate Change in psychomotor activity Sleep disturbance Appetite change and corresponding weight change * Introduction of Depression(3) Duration: Symptom and severity criteria are met for at least 2 weeks Severity impairment of social function individual subjective distress undesirable outcomes on oneself * Geriatric Depression Occurred in people aged 65 and above. 10% worldwide population is made up of older adults. Depressive disorder is one of the most common mental disorders in later life. The prevalence of geriatric depression is about 13.5%. Geriatric depression has specific features, which do not accord with the rigid diagnostic criteria. Beekman AT.et al. British Journal of Psychiatry,1999,174:307-11 * Types of Geriatric Depression Endogenous depression Organic mood disorder Dysthymia Adjustment disorder Vascular depression * Vascular Depression — a new category of geriatric depression(1) Hypothesis Damage to end-arteries supplying subcortical striatal -pallidum-thalamus-cortical pathways disrupts the neuro- transmitter circuitry involved in mood regulation, and may cause depress
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