Aza-MichaelAdditionofChalconewith介绍.PDF

Journal of Organic Chemistry Research 有机化学研究, 2017, 5(2), 107-113 Published Online June 2017 in Hans. /journal/jocr /10.12677/jocr.2017.52014 Aza-Michael Addition of Chalcone with Benzotriazole Catalyzed by MCM-41 Immobilized H3PW12O40 Jinghui Yang, Liuzhuang Xing, Shaolei Xie, Xuejian Xing, Yadong Hou, Yang Wu, Yonghai Hui* College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi Xinjiang th th th Received: May 17 , 2017; accepted: Jun. 9 , 2017; published: Jun. 12 , 2017 Abstract In this paper, mesoporous siliceous material MCM-41 supported H PW O (PW) could act as an 3 12 40 efficient catalyst for the aza-Michael addition reaction of chalcone with benzotriazole. As can be seen from a serial of reaction conditions, the ratio of PW and MCM-41 plays a critical role in the reaction, and the best catalyzed result was achieved when using 50 wt% PW/MCM-41, and the yield was up to 98%. All the products were confirmed by NMR techniques. Moreover, the catalyst was also found to exhibit better recyclability. Keywords MCM-41, Phosphoric Acid, Benzotriazole, Chalcone, Michael Addition 介孔分子筛MCM-41固载磷钨酸催化苯并三氮 唑与查尔酮的氮杂迈克加成反应研究 * 杨敬辉，邢刘庄，谢绍雷，邢雪建，侯亚东，吴 阳，惠永海 新疆大学化学化工学院，新疆 乌鲁木齐 收稿日期：2017年5月17 日；录用日期：2017年6月9 日；发布日期：2017年6月12 日 *通讯作者。 文章引用: 杨敬辉, 邢刘庄, 谢绍雷, 邢雪建, 侯亚东, 吴阳, 惠永海. 介孔分子筛 MCM-41 固载磷钨酸催化苯并三氮 唑与查尔酮的氮杂迈克加成反应研究[J]. 有机化学研究, 2017, 5(2): 107-113. /10.12677/jocr.2017.52014 杨敬辉 等 摘 要 以介孔分子筛MCM-41 固载磷钨酸为催化剂，对苯并三氮唑与查尔酮进行了氮杂迈克加成的催化研究。 经过条件筛选，发现MCM-41 中的磷钨酸负载量对该反应体系有很大的影