生物材料概述117Lecture011706课件.pptVIP

Class Structure CLASS: Tu/Th: 12:30-2pm 203 McLaughlin Hall /ME117 Discussion: Mondays, 203 Mclaughlin. Mechanics and design will be taught in discussion. You are responsible for all material presented in discussion. Office Hrs (Prof. Lisa Pruitt):Tuesdays 3-4:30 or by appointment,5134 EH, lpruitt@me Teaching Assistants: Arun Chawan, Jevan Furmanski, Shikha Gupta, Sheryl Kane, and Cheng Li (office hrs TBA) Course components: HW (25%), EXAMS, April 11/13 (25%), TERM PROJECT (50%) **No late homework excepted. All HW is to be prepared professionally (typed). Assignments will be marked down for grammatical errors. This year our class is webcast. Please use microphones when asking questions. Reader: CopyWorld Course Goals Assessment of structure and mechanical functions of load bearing tissues and their replacements. Examination of biocompatibility of biomaterials and host response to structural implants. Quantitative treatment of biomechanical issues and constitutive relationships of tissues and their replacements. Material selection for load bearing applications including orthopedics, dentistry, cardiology and reconstructive surgery. Mechanical design for longevity of devices Understanding of legal and ethical aspects of medical devices. Course topics Overview of medical devices, FDA regulatory issues, biocompatibility and sterilization technology Biomechanical properties: isotropy/anisotropy, stiffness, bending stresses, contact stresses, multiaxial loading, plasticity, fatigue, fracture, wear, corrosion, design issues. Orthopedics, Dental, Cardiovascular, and Soft Tissue Reconstruction. Case studies. Orthopedics ORTHOPEDICS TISSUES AND BIOMATERIALS: Structure and function of orthopedic tissues. Bone, cartilage, intervertebral discs. Total joint replacements, Spinal implants, Fracture Fixation. Mechanisms for damage and disease. Clinical treatments. Case Studies: 1. Sulzer recall-good manufacturing practice, legal and ethical