解读动脉粥样硬化事 件链—培训课件.pptVIP

1 ) That in the earliest lesions, the fatty streaks, most of the lipid was found in cells containing large numbers of lipid-containing vacuoles (foam cells) ( Fig. 2 ). These were Sudan positive and contained birefringent droplets (the liquid crystals of cholesterol esters). Note that the endothelium over the lesion appears to be intact. That the very earliest lesions appeared at the root of the aorta and in the aortic arch and then proceeded caudally ( Fig. 3 ). That over long periods of cholesterol feeding therewas ultimately deposition of connective tissue (conversion of the fatty streak