10.药物分析授课教案（示例）.docVIP

10. 药物分析授课教案(示例) Chapter 3 Test for Impurity 本文档由【中文word文档库】提供，转载分发敬请保留本信息； 中文word文档库免费提供海量范文、教育、学习、政策、报告和经济类word文档。 Purpose: 1. To master the sources and category of impurities, the definition and calculation of limit tests. 2. To master the principles and methods of the tests for chloride, sulfate, iron, arsenic, clarity of solution, heavy metals, loss on drying, residue on ignition and so on. Outlines： 1. The conception, sources and category of impurities, the definition and calculation of limit tests. 2. The principles and methods of the tests for general impurities: chloride, arsenic, heavy metals, loss on drying, residual solvents. 3. The methods of the tests for specified impurity: utilization of difference in physical or chemical property. Advance： Application of modern analytical methods and techniques in limit test. Highlights： 1．The origins of impurities, calculation of limit tests. 2．Detection methods of chloride, arsenic and heavy metals. Difficult points: 1. The principle of the arsenic test. 2. The principles of various thermal analyses. Suggestion to improve the teaching The lecture on the methods of impurity test should be combined with experiment. Questions for review 1. What is the representative metal in the heavy metal test? How many kinds of the chromogenic agents used in the heavy metals tests? What are the methods of heavy metals tests? 2. The principles, methods and the calculation formula of chloride tests in China pharmacopoeia. 3. The contents of drug impurity test. (Including the sources and category of impurities, and calculation of limit tests.) Teaching aids and equipments: Computer and projection. 第三章 　药物的杂质检查 教学目的 1.掌握药物中杂质的来源和分类，杂质限量的定义和计算； 2.掌握氯化物、硫酸盐、铁盐、重金属、砷盐、溶液颜色、易炭化物、澄清度、炽灼残渣、干燥失重、有机溶剂残留量等检查项目的原理和方法。 本章讲授提纲及学时分配 （2小时） 一、杂质的概念及杂质的来源、杂质的分类，掌握杂质限量检查方法的原理和限量计算。 二、一般杂质检查方法和原理 1.氯化物 2.重金属 3.砷盐 4.干燥失重 5.有机溶剂残留量检查的原理和方法 三、特殊杂质检查的方法 1.利用物理性质的差异 2.利用化学性质的差异 本课程学科的新进展 现代仪器分析手段用于药物微量杂质的检查 本章内容的重点 重点：1．药物杂质来源，限量检查及计算 2．氯化物、重金属、砷盐的检查方法 本章