药理学讲义04 Drug Efficacy.pptVIP

Chapter 4Factors AffectingDrug Efficacy影响药效的因素 Main Factors Affecting Drug Efficacy Age 年龄1.1. Children 孩子们 1.2. The Elderly 老年人 2. Gender 性别 3. Genetic Factors 基因 4. Individual Variations 个体 5. Time of Administration 时间 6. Main Drug Interactions 相互作用 7. Tolerance 耐受性 8. Placebo Effects 无效对照剂 Double-Blind Trials Study Questions * * 1. Age 年龄 2. Gender 性别 3. Genetic Factors 基因 4. Individual Variations 个体 5. Time of Administration 时间 6. Drug Interactions 相互作用 7. Tolerance 耐药量 8. Placebo Effects 无效对照剂 The clearance of caffeine, a pattern observed for many drugs Metabolic clearance is weak