三子丸化学成分和药理作用的研究进展.pdfVIP

天然产物研究与开发Nat Prod Res Dev 2008，20：543047，493 文章编号：1001-6880(2008)01-0543-06 三子丸化学成分和药理作用的研究进展 瓦妮达 ，一，张巧艳 ，秦路平h，周秀佳 第二军医大学药学院生药学教研室，上海200433； 上海中医药大学生药学教研室，上海201203 摘 要：三子丸是由三种果实类中药，即五味子、蛇床子和菟丝子。组成的中药复方，临床上主要用于治疗虚证， 多用于男性患者的肾气虚证。本文综述了三子丸复方中三味中药的化学成分，分析方法及其生物活性的研究 进展，为三子丸的进一步开发利用提供了有力依据。 关键词：中药复方；三子丸；五味子；蛇床子；菟丝子 中图分类号：Q946．91；R285 文献标识码：A Chemical Constituents and Biological Investigations on the Ingredients of Sanziwan WANIDA Caichompoo ，ZHANG Qiao—yan ，QIN Lu．pingh，ZHOU Xiu-jia2 Department ofPharmacognosy，School ofPharmacy，Second Military Medical University， Shanghai 200433，China； Department ofPharmacognosy，Shanghai University of Traditional Chinese Medicine， Shanghai 201203，China Abstract：Sanziwan，a recipe of traditional Chinese medicine，has been used clinically for treating consumption diseases and consumption of the kidney-qi(in male patients)．It consists of 3 components；the fruit of Shisandra chinens~ (Turcz．)，the fruit of Cnidium monnieri(L．)Cuss．and the seeds of Cuscuta chinens~Lain．This review paper considers briefly the chromatographic methods involved and several pharmacological studies with the ingredients of Sanziwan for- mtdation．It focuses on chemical constituents，analytical methods for the determination of the constituents of the ingredi— ents and also their biological activities． Key words：traditional Chinese formtdation；Sanziwan；Shlsandra chinensis(Turcz．)；Cnidium monnieri(L．)Cuss．；Cus- cttta chinensls Lam． nation of compatible ingredients was generalized by I