糖尿病肾病患者血循环激肽释放酶1水平及其临床意义的研究.pdfVIP

Blood circulating level of kallikrein 1 and its significance in patients with diabetic nephropathy ABSTRACT Objective Although patients with diabetic nephropathy(DN) strict metabolic control and strict treatment of hypertension, DN progress maintained a serious clinical problem. More and more evidence that the DN is a multi-factor disease, it’s pathological mechanism is unclear today. Recent studies have confirmed that kallikrein-kinin system(KKS) plays an important role in the DN progress.KLK1 play in the diabetic state in ad