支气管肺炎患儿血清C.docVIP

支气管肺炎患儿血清C-反应蛋白测定的临床意义 【摘要】目的：探讨支气管肺炎患儿血清C-反应蛋白(CRP)测定的临床意义。方法：对73例支气管肺炎患儿(细菌感染组39例和非细菌感染组34例)及40例对照组分别进行CRP、白细胞(WBC)计数及其分类检测，并对结果进行了统计学分析。结果：细菌感染组血清CRP和WBC计数明显高于非细菌感染组和对照组(P均0.01);非细菌感染组血清CRP与对照组比较无显著性差异(P0.05);细菌感染组CRP浓度与WBC计数呈正相关(P0.01)，该组经抗生素治疗，疾病控制后血清CRP和WBC计数明显低于控制前(P均0.01)。结论：支气管肺炎患儿检测CRP浓度对鉴别细菌和非细菌感染，判断病情变化以及疗效观察具有一定的临床价值。 　　【关键词】 支气管肺炎;C-反应蛋白;WBC计数 　　Determination and Clinical Significance of Peripheral Blood C-reactive Protein in Children with Bronchopneumonia 　　DONG Yu-lin,CAO Xiang-hong 　　Yanan Hospital,Kunming,Yunnan 650000,China 　　Abstract：Objective The discussion bronchopneumonia baby blood serum C- response protein (CRP)determines clinical significance.Methods (Bacterial infection group 39 examples and non-bacterial infection group 34 examples)and 40 example control groups carry on CRP, the white blood cell to 73 example bronchopneumonia baby(WBC)to count separately and the classified examination, and has carried on statistics analysis to the result. Results Bacterial infection group blood serum CRP and the WBC counting is higher than the non-bacterial infection group and the control group obviously(P0.01); Non-bacterial infection group blood serum CRP and the control group compare the non-significance difference(P0.05);Bacterial infection group CRP density and WBC counting present related(P0.01), this group after the antibiotic treatment, before after disease controls, blood serum CRP and the WBC counting is lower than the control, obviously(P0.01).Conclusion The bronchopneumonia baby examines the CRP density to distinguish the bacterium and the non-bacterial infection, the judgment condition change as well as the curative effect observation has certain clinical value. 　　Key words:Bronchopneumonia;C-responds the protein;WBC counts 　　C-反应蛋白(CRP)是一种由肝脏合成的急性时相蛋白，在组织损伤和炎症反应的急性期，含量急剧升高，病情好转时很快下降。可鉴别细菌感染和非细菌感染[1]。支气管肺炎是儿童常见的疾病，快速、准确鉴别其感染的病原体(细菌和非细菌)对临床治疗有极其重要的意义。为此，本文对73例支气管肺炎患儿(细菌感染者39例和非细菌感染者34例)及40例对照组分别进行CRP、白细胞计数及其分类检测，现将结果报道如下 　　1 对象与方法 　　1.1 研究对象