参麦注射液对脑出血大鼠神经细胞线粒体dna缺失及凋亡相关基因表达影响的实验研究.pdfVIP

减轻线粒体DNA缺失。提示参麦注射液可能通过抑制线粒体DNA缺失减轻 脑出血后迟发性神经细胞损伤。 关键词：参麦注射液：脑出血；神经元凋-b；凋亡相关基因；线粒体 DNA The oftheEffectsof on Shenmai Study Injection Experimental Deletionand theNeuronalMitochondria-DNA Related Apoptosis in Intracerebral Gene BrainAfter Rat Hemorrhage Expression Postgraduate：LiXiaofeng Advisor：He Zeyun rat With modelswithintracerebral Sprapue—Dewley observedtheeffectsof offthe research Shenmai(SM)Injectionpathologic oftheneuronalstructurein CAl of changes hippocampalgyrusareas，expression Bcl一2 Bax and mRNA mRNA， mRNA，PDGF—A mRNA，C—myc mitochondria．DNAdeletionintheareasaroundthehematoma． Results： 1．Theeffectonthe ofneuronalstructure pathologicchanges inhippocampal areasinratmodels with afterICHthe CAl in rats，We gyrus ICH．7days examinedthebraintissuestherats of andfoundthatSM had effectson Injection the cells inthe CAl