回回药方失荅剌知丸治疗腔隙性脑梗死患者认知功能障碍的疗效观察.docVIP

《回回药方》失荅剌知丸治疗腔隙性脑梗死患者 认知功能障碍的疗效观察★ 付慧玲1 李方2 贾孟辉1，3刘丽1曹丽翠1左艳丽4 于凌志4李占涛4苏丹4 （1.宁夏医科大学第二附属医院 宁夏银川 750001 2.银川市兴庆区永安中医回医医院 宁夏银川 750000 3.回医药现代化省部共建教育部重点实验室 宁夏银川 750004 4.宁夏医科大学中医学院 宁夏银川 750004） 摘要：目的 观察失荅剌知丸治疗腔隙性脑梗死患者认知功能障碍的临床疗效。 方法 将80例腔隙性脑梗死患者随机分为对照组及治疗组各40例，两组患者合并有高血压、糖尿病、高血脂者予对症治疗。对照组静滴血栓通注射液500mg，每日1次，治疗14天；治疗组静滴血栓通注射液，同时口服失荅剌知丸，1日2次，10g/次，治疗14天；对两组患者治疗前和治疗后进行蒙特利尔认知评估量表（MoCA）评分。结果 治疗前两组MoCA评分两组差异无统计学意义（P﹥0.05）；治疗后治疗组MoCA评分差异有统计学意义（P﹤0.05；对照组治疗前后无显著差异（P﹥0.05）。结论 回药方失荅剌知丸对腔隙性脑梗死患者认知功能障碍有明显改善作用。 关键词：失荅剌知丸；腔隙性脑梗死；认知功能障碍；M oCA The curative effect observation of Shi da la zhi wan treatment?on ischemic stroke of cognitive disorder Jao Yang1 Li Fang2 Jia Meng hui3 Cao Li cui3 Zuo Yan li4 Yu Lin zhi4 (1.The ShaPotou hospital of Ningxia of Zhongwei 2.Yongan hospital of ?traditional Chinese medicine and Hui medicine 3.The first peoples hospital of Yinchuan 4.Ningxia medical university institute of traditional Chinese medicin) Abstract: objective?To investigate The curative effect observation of Shi da la zhi wan treatment?on ischemic stroke of cognitive disorder.Methods?80 cases ischemic stroke were randomly divided into the control group and the treatment group, 40 cases in each group.Two groups of patients with high blood pressure, diabetes, hyperlipidemia to symptomatic treatment.tthe control group were treatment with?XueShuanTong injection 500 mg,once per day for 14 days;the treatment group were given XueShuanTong injection and Shi da la zhi wan,10g/time,twice per day for 14 days.Cognitive function and the amelioration of intelligence were assessed before and after treatment.Results The montreal cognitive assessmentof score both groups before treatment had no significant difference (P0.05).Treatment group after treatment of MoCA score difference was statistically significant (P ﹤0.05);The control group before and after treatment had no significant difference (P﹥0.05).Conclusion The Shi da la