冠心病患者血清瘦素水平的测定及意义.pdfVIP

3。苓嚣髓舅《蛊清瘦素永乎觅较，嚣心病缓贯性盎清瘦素永等 照组贯性盘滂瘦素拳平(4。筠土3。04)n∥心，安缝盎滂疫素永莘 (9．43±5．49)n∥lIll。冠心瘸组和对照组女性血清瘦素水平均明 显高予男往(pO．05，PO。01)。 4．男性受试者中，冠心病组血清瘦索水平(8．40士8。31)ng／ 菇裔予黯慧组矗清瘦素承警(4．56±3．04)n∥越，P《Q。舔。去 除对照组中血糖6．1mmol／L的受试者10例，对照组余25例的 血渍瘦素东乎(4．69土3．51)ng／．a，冠心瘸组识离予对照蕴，P 0．05。 5．勇往受试者中，冠心瘸缓及对慧缀巍清痰索永平均与BblI ， 结 论÷ 1．所有受试者的堕董塑塞好与BMI呈显藩正相关，肥胖者 体态襻在内源性瘦紊抵藐。 ， 2-女性搬涛瘦索水平比男性磁，性激豢参与瘦素的代谢。 3．藩心病缢蛊潺瘦素求乎离予薄照纽，捷承瘦素爨蒺示嚣心 病的危险因素之一。 关键镶：冠心癔；瘦素≯ ·2· in Abstract EnOCh Objective Americanscholars obese in1994．Its successfulclonedgene pro- tein floon hasbeen discovered。Since product，leptin，was then，there increase in metabolicroleinhumans．Thereare interestits potential of andits disea- great inthe obesity related significance investigation as and c砌ova8cular me- ses，such tabolism is in of involvedthe bodyweihgt syndrome．Leptin regulation andmetabolisminmanandalsobeinvolvedinthe of pathophysiology insulin is the resistance associatedwiththe syndrome，which coronary heart