丹红、硫酸镁注射液联用治疗慢性肺心病急性加重期疗效观察.docVIP

丹红、硫酸镁注射液联用治疗慢性肺心病急性加重期疗效观察[摘要] 目的：观察丹红和硫酸镁注射液联用对慢性肺心病急性加重期的疗效。方法：选择我院78例慢性肺心病急性加重期患者，将其随机分为治疗组（n=39）和对照组（n=39）。两组均给予常规西医综合治疗，治疗组在常规治疗基础上加用丹红和硫酸镁注射液静脉滴注，2周为1个疗程。比较两组患者的疗效及治疗前后血气分析、肺动脉压方面有无差异。结果：两组都有明显疗效，但与对照组比较，治疗组在肺功能及血气结果的改善更加显著，肺动脉压的下降更明显，差异有统计学意义（P＜0.05）。结论：丹红和硫酸镁注射液联用对治疗慢性肺心病急性加重期有显著疗效 [关键词] 肺心病；丹红注射液；硫酸镁注射液 [中图分类号] R541.5 [文献标识码] A [文章编号] 1673-7210（2011）12（a）-087-02 Observation of curative effect on Danhong Injection and Magnesium Sulfate Injection in the treatment of chronic cor pulmonale in acute exacerbation DONG Fang, YANG Qinqing, MA Ruibin, KE Ying Department of Respiration and Gastroenterology, Hospital of Armed Police in Xinjiang Corps, Xinjiang Uygur Autonomous Region, Urumqi 830000, China [Abstract] Objective: To observe the effect of Danhong Injection and Magnesium Sulfate Injection in the treatment of chronic cor pulmonale in acute exacerbation. Methods: 78 patients with chronic cor pulmonale in acute exacerbation of our hospital were randomly divided into treatment group (n=39) and control group (n=39). The control group was treated with routine western medicine, the treatment group was additionally given Danhong Injection combined with Magnesium Sulfate Injection, 2 weeks as a course. The effects and blood gas analysis and pulmonary artery pressure before and after treatment were compared between the two groups. Results: Both groups had obvious effects. Compared with the control group, patients in the treatment group had a better improvement in pulmonary function and blood gas analysis, as well as a more marked decline in pulmonary artery pressure. All these measurements had significant differences between the two groups (P＜0.05). Conclusion: There is an obvious therapeutic effect of Danhong Injection and Magnesium Sulfate Injection in the treatment of chronic cor pulmonale in acute exacerbation. [Key words] Pulmonary heart disease; Danhong Injection; Magnesium Sulfate Injection 慢性肺源性心脏病是由肺组织、肺血管或胸廓的慢性病变引起肺组织结构和（或）功能异常，产生肺血