Integrating genomics, bioinformatics, and classical genetics to study the effects of recombination on genome evolution：（整合基因组学、生物信息学和古典遗传学研究重组基因组进化的影响）.pdfVIP

Integrating Genomics, Bioinformatics, and Classical Genetics to Study the Effects of Recombination on Genome Evolution John A. Birdsell Department of Ecology and Evolutionary Biology, University of Arizona, Tucson This study presents compelling evidence that recombination significantly increases the silent GC content of a genome in a selectively neutral manner, resulting in a highly significant positive correlation between recombination and ‘‘GC3s’’ in the yeast Saccharomyces cerevisiae. Neither selection nor mutation can explain this relati