消化内科门诊胃食管反流病临床分析.docVIP

消化内科门诊胃食管反流病临床分析 　　【摘要】 目的 研究分析消化内科门诊治疗胃食管反流病的措施与临床效果。方法 86例消化内科门诊收治的胃食管反流病患者， 随机分为对照组和观察组， 每组43例。对照组应用雷尼替丁进行治疗， 观察组则在对照组治疗基础上联合使用奥美拉唑治疗。对比两组患者临床效果。结果 观察组治疗总有效率95.3%显著高于对照组76.7%， 差异具有统计学意义（P0.05）， 治疗后两组症状积分均较治疗前改善， 且观察组改善情况优于对照组， 差异均具有统计学意义（P0.05）。结论 消化内科门诊治疗胃食管反流病患者给予雷尼替丁的同时联合使用奥美拉唑能显著提高临床治疗有效率， 改善患者的临床症状， 且还不会增加药物不良反应， 可在基层推广应用 【关键词】 消化内科；胃食管反流病；临床分析 DOI：10.14163/j.cnki.11-5547/r.2016.35.053 【Abstract】 Objective To research and analyze measures of gastroesophaeal reflux disease in digestive system department outpatient and their clinical effect. Methods A total of 86 gastroesophaeal reflux disease patients in digestive system department outpatient were randomly divided into control group and observation group， with 43 cases in each group. The control group received ranitidine for treatment， and observation group also received omeprazole for treatment. Clinical effect was compared between two groups. Results The observation group had higher total treatment effective rate as 95.3% than 76.7% in control group， and the difference had statistical significance （P0.05）. Both groups had better symptom scores after treatment than before treatment， and observation group had better improvement than control group， and the difference had statistical significance（P0.05）. Conclusion Ranitidine combined with omeprazole for treatment of gastroesophaeal reflux disease in digestive system department outpatient can effectively enhance clinical curative effect and improve clinical symptom of patients， without increasing adverse drug reactions. So this method can be applied in grassroots. 【Key words】 Digestive system department； Gastroesophaeal reflux disease； Clinical analysis 反流性胃食管炎是消化?瓤浦幸恢直冉铣＜?的疾病。该种疾病会引发患者胃肠道功能障碍， 由此引起内容物反流进入到食管中， 损伤食管及其黏膜[1-5]。属于一种炎性病变。检查该种疾病的常用设备为内镜。内镜检查的结果可以说是胃食管反流的金标准。如患者食管黏膜遭受损伤， 就会在内镜上显示出来。研究中发现大约有80%左右的胃酸反流患者会出现反流性食管炎。本文选取2013年3月～2015年3月本院消化内科门诊收治的胃食管反流病患者86例。研究分析消化内科门诊治疗胃食管反流病的措施与临床效果， 现报告如下 1 资料与方法 1. 1 一般资料 选取2013年3月～2015年3月本院消化内科门诊收治的