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生物衍生骨与骨髓间充质干细胞复合修复免桡骨大段缺损.pdfVIP

生物衍生骨与骨髓间充质干细胞复合修复免桡骨大段缺损.pdf

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中国组织工科研究与临床康复 第13:# !fj 3 jf!J 2009 - 01 唰 15 出版 Joumal of Clinical Rehabifitative Tissue Engineering Research January 15, 2009 Vol.13, NO.3 @需死定基础 生物衍生骨与骨髓间充质干细胞复合修复兔挠骨大段缺损食 朱肖奇嚣,贺用非Ll,马雪峰1 ,郭溅1 Bio-derived bone compound with marrow stromal stem cells to repair large segmen阳I radlal bone defec幅 in rabbits 1 1 Zhu Xiao-qi 气 He Yong-Ii飞 Ma Xue-feng , Guo Hao Abstract 自ACKGROUND: The bio-derived sca衍。Id materials have the similar structure and microenvironment with the autologous bon晤, Department of thus they are promising to apply. Orthopaedics, Shenzhen Baoan OBJECTIVE: To observe the feasibility 01 repairing large segmenl radial defects with bio-derived bone ∞mbined wilh bone Hospital, Southem marrow stromal stem cells , and 10 compare the curative 白ffects with bio-derived bone alone. Medi佣I Universlty, 。巨SIGN, TIME AND S巴TTING: 问andomization design animal controlled trials were performed at the laboratory of Life Science Shenzhen 518101 , Guangωng College 01 Nanhua University Irom January 2007 10 January 2008. Pro\lince, China; MAT医院IALS: 日io-derived bone scaffold was prepared through a se川al of physical and chemical processes, including degreasing, Post-doctoral deproteinization , pa叫ial decalcilication and Ireeze drying. Bio-derived bone scaffold was then co-cultured with induced bone 问esearch Cente民

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