8个国家55ICU的HAI.pdfVIP

Annals of Internal Medicine Article Device-Associated Nosocomial Infections in 55 Intensive Care Units of 8 Developing Countries ´ Victor D. Rosenthal, MD; Dennis G. Maki, MD; Reinaldo Salomao, MD; Carlos Alvarez-Moreno, MD; Yatin Mehta, MD; ¨ Francisco Higuera, MD; Luis E. Cuellar, MD; Ozay Akan Arikan, MD; Re´douane Abouqal, MD; and Hakan Leblebicioglu, MD, for the International Nosocomial Infection Control Consortium* Background: Health care–associated infections from invasive med- greatest risk (41% of all device-associated infections or 24.1 cases ical devices in the intensive care unit (ICU) are a major threat to [range, 10.0 to 52.7 cases] per 1000 ventilator days), followed by patient safety. Most published studies of ICU-acquired infections CVC-related bloodstream infections (30% of all device-associated have come from industrialized western countries. In a Centers for infections or 12.5 cases [range, 7.8 to 18.5 cases] per 1000 cath- Disease Control and Prevention (CDC) National Nosocomial Infec- eter days) and catheter-associated urinary tract infections (29% of tions Surveillance (NNIS) System report, the U.S. pooled mean rates all device-associated infections or 8.9 cases [range, 1.7 to 12.8 of central venous catheter (CVC)–related bloodstream infections, cases] per 1000 catheter days). Notably, 84% of Staphylococcus ventilator-associated pneumonia, and catheter-associated urinary aureus infections were caused by methicillin-resistant strains, 51% tract infections were