甲基营养型芽孢杆菌可湿性粉剂配方的优化_李学红.pdfVIP

第38 卷第6 期 煤 炭 与 化 工 Vol.38 No.6 2015 年 6 月 Coal and Chemical Industry June 2015 问题探讨 甲基营养型芽孢杆菌可湿性粉剂配方的优化 李学红 （华北制药集团 爱诺有限公司，河北 石家庄 052 165） 摘 要：为提高甲基营养型芽孢杆菌可湿性粉剂 （WP） 的润湿性和悬浮率，通过助剂筛 选、正交试验设计优化了制剂配方。结果表明，以萘磺酸钠甲醛缩合物 （NNO）作为分散 剂和烷基丁二酸磺酸盐 （CB- 102）作为润湿剂的复配助剂，助悬浮和助润湿效果明显；通 过正交试验设计确定了该可湿性粉剂中助剂的最佳添加比例为：1% 轻质碳酸钙，6% CB- 102 和6% NNO。以此为配方制取的可湿性粉剂悬浮率可达到74.7% ，润湿时间48.2 s，pH 值为 6.89 ，指标均可达到指定标准；田间试验结果表明，甲基营养型芽孢杆菌可湿性粉剂稀释 500 倍液和800 倍液对黄瓜灰霉病的防效分别达到78.8%和74.7% 。 关键词：甲基营养型芽孢杆菌；可湿性粉剂；悬浮率；润湿时间；黄瓜灰霉病 中图分类号：TQ450.6 文献标识码：A 文章编号：2095- 5979 （2015）06- 0046- 05 Formulation Optimization of Bacillus Methylotrophicus Wettable Powder LI Xue- hong ( NCPC Ainuo Corp oration Ltd., Shij iazhuang 052 165, China ) Ab stra ct ：To improve the wettability and the suspensibility of bacillus methylotrophicus wettable powder （WP ）, the formulation of bacillus methylotrophicus WP was optimized by additives screening and orthogonal experiment. The results show that the compound adjuvant which is composed by NNO as dispersant and CB- 102 as wetting agent can improve the suspensibility and wetting effects. Orthogonal experiment design was used to determine the optimum mixture proportion of the adjuvants in WP: 1% of light calcium carbonate （LCC ）, 6% of CB- 102and 6% of NNO. Based on the formulation,the suspensibility of WP can reach to 74.7% , wetting time is 48.2 s and pH value is 6.89, the index all satisfy the proper standard. The results of field experiment show that the control efficacy of bacillus methylotrophicus WP dilute 500 times and 800 times o