多形性胶质母细胞瘤MR弥散张量成像应用研究.pdfVIP

DOI :10.13929/j.1003 -3289.2008.07.044 · 992 · 2008 24 7 　Chin J Med Imaging Technol, 2008, Vol 24, No 7 　 Diffusion tensor MR imaging of glioblastoma multiforme 1 1 * 2 1 1 WU J ing , DA I J ian-p ing , J IA N G Tao , L I S hao-w u , GA O Pei-y i (1.Imag ing Cen ter of N euroscience, 2.G ioma Therap y Cen ter , B eij ing Tiantan H osp ita , Cap ita Med ica Un iversity , B eij ing 100050, Ch ina ) [ Abstract] 　Objective　To eval ate the val e of f ractional anisotropy (FA )and apparent diff sion coefficients (ADC)meas- rement in differentiating t mor, edema, and normal w hite matter regions and w hether they are helpf l in differentiating t mor invasion.Methods　Fo rteen patients with glioblastomas m ltiforme nderw ent conventional M R, cont rast-enhanced str ct ral and diff sion tensor MR imaging before therapy.T mor, edema, and normal-appearing white matter regions were determined on contrast-enhanced T 1-w eighted str ct ral images, T2-weighted str ct ral images.FA and ADC w ere meas- red in each tiss e type in the ADC maps and FA maps.Differences in these val es among the tiss e types w ere assessed -3 2 with a standard analysis of variance.Results　ADC w as highest in the necrotic t mor core (2.07 ±0.631)× 10 mm / s, -3 2 -3 2 follow ed by edema region (1.39±0.164)× 10 mm / s, enhancing t mor core (1.13±0.187)× 10 mm / s, enhancing