深静脉血栓的防治.pptVIP

* While arterial thrombosis is generally associated with rupture of an atherosclerotic plaque, venous thrombosis is usually the result of stasis. Venous thrombi mostly form in regions of slow or disturbed blood flow, typically the large sinuses and valve cusp pockets in the deep veins of the calf. Stasis increases the risk of thrombosis by impairing the clearance of activated coagulation factors and limiting the accessibility of thrombin to thrombomodulin, a protein found at highest levels in the capillaries and which inactivates thrombin. Factors which promote stasis and so can increase