医学电子书系列Chapter 7 – Wound Healing.pdfVIP

CHAPTER 7 WOUND HEALING Mimi Leong and Linda G. Phillips All three phases may occur simultaneously, and the phases may tissue injury and response overlap with their individual processes (Fig. 7-1). wound-healing phases abnormal wound healing Inflammatory Phase the relationship between immunity and wound healing During the immediate reaction of the tissue to injury, hemosta- or regeneration sis and inflammation occur. This phase represents an attempt to fetal wound healing limit damage by stopping the bleeding, sealing the surface of the wound dressings wound, and removing any necrotic tissue, foreign debris, or other therapies bacteria present. The inflammatory phase is characterized by new horizons increased vascular permeability, migration of cells into the wound by chemotaxis, secretion of cytokines and growth factors into the wound, and activation of the migrating cells (Fig. 7-2). The treatment and healing of wounds are some of the oldest Hemostasis and Inflammation subjects discussed in the medical literature. Yet despite knowl- During an acute tissue injury, blood vessel damage results in edge of the steps involved, the exact