膀胱癌术后联合采用介入治疗和膀胱灌注预防肿瘤复发和转移的临床应用价值探讨.pdfVIP

。236。 ·论著· 膀胱癌术后联合采用介入治疗和膀胱灌注预防 肿瘤复发和转移的临床应用价值探讨 吴渭贤，朱希松，孔宏伟 (浙江省衢州市人民医院放射科，浙江衙州 324000) 【摘要】 目的 探讨膀胱癌术后联合采用介入治疗和膀胱灌注预防肿瘤复发和转移的临床应用价值。方 法将108例膀胱癌患者随机分为两组。52例于手术后单纯行定期膀胱灌注(单纯灌注组)；56例于手术后联 合采用介入治疗和膀胱灌注(介入灌注组)。对两组患者进行1～3年的跟踪比较。结果A组术后1年内复发 入灌注组患者3年内复发率、转移率和病死率均较单纯灌注组显著降低，差异均有统计学意义(Po．05或 P0．01)。结论 膀胱癌术后联合采用介入治疗和膀胱灌注对预防术后肿瘤复发、转移和延长患者生命具有 十分重要的意义。 【关键词】膀胱肿瘤；手术；介入治疗；膀胱灌注 中围分类号：R737．14文献标识码：A 文章编号：1008—9691(2008)04—0236—03 Theclinicalvalueofinterventionai andIntraveslcalinstillationfor chemotherapy preventingpostoperative WU recurrenceandmetastasisofcancerin bladderWei—xian，ZHU urinary Xi—song，KoNGHong—wei． of ofQuzhou DepartmentRadiology，People’sHospital City，Ouzhou324000，Zhejiang，China Toevaluatetheclinicalvalueofinterventional andintravesical [Abstract] chemotherapy Objective instillationfor recurrenceandmetastasisofcancerin bladder．MethodsOne preventingpostoperative urinary hundredand with bladdercancerweredividedinto Aand B．Intravesical eightpatientsurinary group group instillationsafter were in A(n一52)andcombinedinterventional surgicaloperationperformedgroup andintravesicalinstillationsafter were in B(砣一56)．The chemotherapy operationperformedgroup patients werefollowedfor1—3 In A，recurrenceoccurredin5 one up years．Results cases(9．62％)within group in23