抗生素对嗜麦芽窄食单胞菌性呼吸机相关性肺炎的疗效分析.pdfVIP

· 982· 医学2007年1】月第27 1塑 』 ! 篓 !： !： ： !： ：! 抗生素对嗜麦芽窄食单胞菌性呼吸机相关性 肺炎的疗效分析 蔡福良， 刘励军 作者单位：215004 江苏，苏州大学附属第二医院急诊科ICU 作者简介：蔡福良(1980一)，男，硕士研究生，研究方向：机械通气与肺保护，E—mail：caifl0907@yahoo．COIl1．Clfl。 通讯作者：刘励军，男，主任医师，教授，硕士研究生导师，急诊科及ICU主任。 [摘要] 目的 评价抗生素对嗜麦芽窄食单胞菌性呼吸机相关性肺炎的疗效，指导临床治 疗。方法 对72例由嗜麦芽窄食单胞菌引起的呼吸机相关性肺炎患者进行回顾性分析，根据是否 抗嗜麦芽窄食单胞菌治疗将人选患者分为非治疗组(34例)和治疗组(38例)，比较两组患者肺炎 的预后。结果 非治疗组治愈5例，显效14例，无效15例，总有效率55．88％；治疗组治愈7例，显 效19例，无效12例，总有效率68．42％。两组患者肺炎预后比较差异无统计学意义(x =1．20， P0．05)。结论 尚不能认为抗生素对嗜麦芽窄食单胞菌引起的呼吸机相关性肺炎有显著疗效。 [关键词] 嗜麦芽窄食单胞菌；呼吸机相关性肺炎；抗生素；疗效 [中图分类号] R 563．8 [文献标识码] A [文章编号] 1002—1949(2007)11—0982—03 Curative effect of antibiotic for ventilator—associated pneumonia infected with stenotrophomonas maitophilia CAI 一liang，LIU Li～jun．Department ofEmergency，the Second Affiliated Hospital of Suzhou University，Suzhou 2 15004，China [Abstract] Objective To evaluate the curative effect of antibiotic for ventilator—associated pneumonia(VAP)infected with stenotrophomonas mahophilia(SM)and provide the evidences for treat— ment．Methods 72 patients were involved in this study and divided into two groups：non～treated group and treated group with antibiotic．To compare the prognosis of patients in two groups．Results There were 34 patients in the non—treated group：5 were cured，14 showed obvious improvement and 15 were ineffec— tive；there were 38 patients in antibiotic treated group：7 were cured，19 showed obvious improvement and 12 were ineffective．There were no significant differences in results between the two groups(x =1．20，P 0．05)．Conclusion There was no evidence that antibiotics are effectiVe for ventilator—associated pneu— monia infected with stenotrophomonas mahopbilia． [Key words] stenotr(】phom0nas mahophilia； Curative ef ct 嗜麦芽窄食单胞菌(stenotrophomonas maho． 州大学附属第二医院ICU符合SM相关的VAP患 philia，SM)为非发酵需氧的革兰阴性杆菌，为条件 者72例，其中