生物信息导论.pptVIP

* * Gene Databases Once a genome is assembled, targeting genic regions is desired Humans: 30,000 genes On order of 1,000’s of bases long * * Gene Databases RefSeq Set of mRNA sequences curated at NCBI Many experimentally validated Some partially validated via ESTs Some computationally predicted * * Gene Databases Give information into gene functionality Alternative splicing of genes Alternative pattern of exons included to create gene product Databases of approved gene names * * Gene Databases RefSeq: NCBI Reference Sequence Project /RefSeq/ AllGenes: GDB / GenAtlas: http://www.citi2.fr/GE