比索洛尔治疗冠心病合并COPD高龄患者对肺功能的影响_童晓玲.pdfVIP

中国药物应用与监测2012年6月第9卷第3期 Chinese Journal of Drug Application and Monitoring, Vol.9, No.3, June 2012 比索洛尔治疗冠心病合并COPD 高龄患者对肺功能的影响 1 1 2 1 （1. 解放军16 1 医院干部病房，湖北 武汉 4300 10 ；2. 解放军16 1 医院医务处，湖北 武汉 童晓玲 ，田海军 ，梁晓明 ，艾 韵 430010 ） [摘要] 目的：根据比索洛尔在治疗冠心病合并慢性阻塞性肺疾病（COPD ）高龄患者中的应用状况，分析其对肺功能的影响， 为临床治疗提供参考。方法：对照组45 例高龄冠心病合并COPD 患者给予常规治疗，治疗组51例在常规治疗的基础上服用 比索洛尔，疗程4 周。观察治疗组与对照组患者的临床症状、心电图、心率及治疗前后VC 、TV 、FVC 、FEV 、FEV % 、MMF 1 1 P 等肺功能数值的变化。结果：比索洛尔治疗组在临床症状、心电图、降低心率等指标方面明显优于对照组（ 0.05 ），治疗前 后两组患者肺功能均无明显变化。结论：比索洛尔对冠心病合并COPD 的高龄老年患者的肺功能无明显影响，且药物不良反 应少。 [关键词] 比索洛尔；冠心病；高龄；慢性阻塞性肺疾病；肺功能 [ 中图分类号] R972+.4 [文献标识码] A [文章编号] 1672 – 8157(2012)03 – 0133 – 03 Effect of bisoprolol on pulmonary function in treatment of senile coronary heart disease patient with COPD 1 1 2 1 TONG Xiao-ling , TIAN Hai-j un , LIANG Xiao-ming , AI Yun (1. Department of Cadre Ward, the 161 Hospital of PLA, Wuhan 430010, China; 2. Department of Medical Services, the 161 Hospital of PLA, Wuhan 430010, China) [ABSTRACT] Objective: According to the effects of bisoprolol in treatment of elderly patients with coronary heart disease and COPD to analyze its effect on lung function, and provide reference for treatment in clinic. Methods: A total of 51 senile patients with coronary heart disease and COPD added bisoprolol for 4 weeks besides the routine treatment, while 45 patients were arranged as control group. Their symptoms, electrocardiogram, heart rate of patients, the changes of VC, TV, FVC, FEV , FEV %, MMF value 1 1 of pulmonary function before and after treatment were observed. There were significant d