（参考翻译）11.1-皮肤性病学 eczema-huangkun.pptVIP

* * * * * * * ECZEMA 湿疹 Huang Kun, MD, PhD Department of Dermatology The First Affiliated Hospital, Chongqing Medical University Definition 1 Etiology and pathogenesis 2 Clinical manifestations 3 Diagnosis and differential diagnosis 4 Treatment 5 Definition 定义 Eczema = Ekzein, “boil out” “pruritic papulovesicular process, which in its acute phase is associated with erythema and edema and which in its chronic phase, while retaining its papulovesicular feature, is dominated by thickening, lichenification and scaling.” Definition 定义 Eczema = Ekzein, “boil out” “丘疹水疱性和搔痒性病程, 急性期表现为红疹和水肿，而在慢性期，除保留上述症状外, 还主要表现为病灶增厚, 苔藓样硬化 和鱼鳞样变.” Etiology and pathogenesis Internal factors External factors Hereditary tendency 遗传倾向 eczema Etiology and pathogenesis Internal factors External factors Hereditary tendency 遗传倾向 chronic infection block of blood circulation change of endocrine 内分泌 and metabolism 代谢 Etiology and pathogenesis Internal factors External factors Hereditary tendency 遗传倾向 eczema IgE Clinical Manifestations What are the symptoms of acute, subacute 亚急性 and chronic eczema? Acute Subacute Chronic Acute Subacute Chronic allergen Acute eczema Intensely itching 剧烈瘙痒 Primary and multiform lesions 原发及多样性损伤 The boundary is not clear 边界不清 Place symmetrically, mostly on exposed areas 对称分布，最常见于暴露在外的区域 Infection 感染 Primary and multiform Erythema 红疹, papulovesicle 丘疹水泡, exudation 渗出, erosion 侵蚀 Place symmetrically 对称分布, appear anywhere on the body, mostly on the face, neck, elbows 肘, wrists 腕, breast 胸部, scrotum 阴囊, backs of the knees and ankle 踝. Subacute eczema relieve from the above symptoms 上述症状减轻 colors of eruption become dark 疹变为黑色 scales 鳞屑 touch allergic things again, acute condition will appear repeatedly 再次接触致敏物质，急性症状将复发 become chronic eczema 转变为慢性湿疹 Chronic eczema always coming from acute or subacute eczema 多由急性和亚急性湿疹发展而来 the lesions become thicken, rough and concomitance with pigmentation or depigmentation 病灶增厚、粗糙，伴有或不伴有脱色 This condition can keep for a