血浆同型半胱胺酸和d-二聚体水平与急性期脑梗死各亚型的关系.pdf

/index.php/gjtm Global Journal of Traditional Medicine，2014,Vol.2,No.2 Plasma homocysteine(Hcy) and D-dimer levels in patients with differernt subtype of acute cerebral infarction: a correlation study 1 1 1 1 1 1 2 Ming Li ,YU Da-lin ,TANG Xian-yong ,FANG Xian-wen ,YONG Xing ,LI Hui-ying ,XIAO Jun 1The Second Peoples Hospital of Shuangliu, Chengdu, China 2Sichuan Provincial Peoples Hospital, Chengdu, China Received: May 22, 2014 Accepted: Jun 5, 2013 Published: Jul 15, 2014 DOI:10.14725/gjtm.v2n2a469 URL:/10.14725/gjtm.v2n2a469 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Purpose-To study plasma homocysteine(Hcy)/D-dimer levels in patients with differernt subtype of acute cerebral infarction for early etiology diagnosis. Methods: The subjects were 246 acute cerebral infarction patients in the first 24 hours of stroke onset at our hospital. We divided them into large –artery atherosclerosis(LAA) group(n=66), small artery occlusion(SAO) group(n=76), cardio embolism(CE) group(n=40),stroke of other demonstrated etiology(SOE) group (n=11)and stroke of other undemonstrated etiology(SUE) group(n=51) according to the TOAST classification. Plasma homocysteine and D-diamer were determined within the first 24 hours of admission, the differences in subgroups and control group(n=121) were analyzed. Results:Plasma homocysteine levels in LAA group were signficantly higher than other groups(P0.05), no differences in non-LAA groups(P0.05);Plasma D-diamer levels in CE group were significant higher than other groups(P0.05), no differenc